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2000年美国科学家Steppan等人,在筛查噻唑烷二酮类(TZDs)药物下调基因时首先发现,由脂肪细胞分泌具有拮抗胰岛素、升高血糖作用的激素称为抵抗素(resistin)。近年来,有关抵抗素基因结构、功能、基因表达,以及与肥胖、2型糖尿病等其他相关性疾病的关系进行了大量研究。本文谨就
In 2000, the American scientist Steppan et al. First screened the genes of thiazolidinediones (TZDs) to down-regulate the gene. First, it was found that the hormone secreted by adipocytes that has the function of antagonizing insulin and elevating blood sugar is called resistin. In recent years, a great deal of research has been conducted on the relationship between the structure, function, gene expression of resistin genes and other related diseases such as obesity and type 2 diabetes. This article just