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脑脊液细胞学作为国际上的一门新兴学科,还仅仅是近20年的事情。近10年来,国外学者在原有脑脊液细胞形态学的光镜和电镜研究基础上,主要引用免疫学方法对脑脊液淋巴细胞亚群的研究,以及细胞化学方法对不同神经系统疾病的脑脊液细胞学研究,均取得了较好成果。尤其是当单克隆抗体技术应用以来,对脑脊液淋巴细胞亚群的深入研究、中枢神经系统肿瘤的诊断,以及脑脊液单核细胞功能的探讨更显示了较好前景。不仅丰富了脑脊液细胞学自身内容,且已成为神经免疫学的一个组成部分。脑脊液细胞与
As a new emerging discipline in the world, cerebrospinal fluid cytology is only a matter of nearly 20 years. In the past 10 years, based on the light and electron microscopy studies of cerebrospinal fluid cell morphology, foreign scholars mainly used the immunological methods to study the cerebrospinal fluid lymphocyte subsets and the cytological methods of cerebrospinal fluid cytology of different nervous system diseases, Have achieved good results. Especially since the application of monoclonal antibody technology, the further research on lymphocyte subsets of cerebrospinal fluid, the diagnosis of CNS tumors and the exploration of cerebrospinal fluid mononuclear cell function have shown a better prospect. Not only enriches the content of cerebrospinal fluid cytology itself, but also becomes an integral part of neuroimmunology. Cerebrospinal fluid cells and