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目的:观察腹腔镜手术联合化疗治疗直肠癌的临床疗效。方法:选取清远市人民医院2014年5月至2015年10月收治的直肠癌患者80例,按随机数字表法分为观察组(40例)采用腹腔镜手术联合化疗治疗,对照组(40例)采取传统开腹手术联合化疗。术后化疗方案选择:氟尿嘧啶联合奥沙利铂。连续治疗3周为1个疗程,3个疗程后比较两组患者临床疗效。结果:观察组临床疗效有效率为97.5%,对照组80%;观察组患者在术中出血量、下床活动时间及住院时间等方面均优于对照组,组间比较,差异具有统计学意义(P<0.05)。观察组并发症发生率17.5%低于对照组47.5%,差异具有统计学意义(P<0.05)。结论:腹腔镜联合化疗治疗直肠癌,手术用时较长,但术后恢复更快,并发症发生率更低。
Objective: To observe the clinical efficacy of laparoscopic surgery combined with chemotherapy for rectal cancer. Methods: Eighty patients with rectal cancer who were treated in Qingyuan People’s Hospital from May 2014 to October 2015 were randomly divided into observation group (40 cases) and laparoscopic surgery group (40 cases) Take traditional laparotomy combined with chemotherapy. Postoperative chemotherapy options: fluorouracil combined with oxaliplatin. Continuous treatment for 3 weeks for a course of treatment, after 3 courses of clinical efficacy of the two groups were compared. Results: The effective rate of clinical curative effect was 97.5% in observation group and 80% in control group. The observation group was superior to control group in terms of intraoperative blood loss, time spent in bed and hospital stay, etc. The differences between the two groups were statistically significant (P <0.05). The incidence of complications in the observation group was 17.5% lower than that in the control group (47.5%), the difference was statistically significant (P <0.05). Conclusion: Laparoscopic combined with chemotherapy for rectal cancer, surgery longer time, but faster recovery after surgery, the complication rate is lower.