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目的 :探讨溃疡性结肠炎 ( UC)临床特征 ,提高对本病的认识及诊治水平。方法 :回顾性分析我院 1 995年～ 1 997年收治的经纤维结肠镜确诊的 1 48例 UC患者的临床特征。结果 :发现UC的住院病例较前有增高趋势 ,男女发病率无明显差异 ,发病平均年龄为 40 .37岁 ,30～ 49岁多发。临床特征有腹泻 ( 80 .41 % )、脓血便 ( 63.51 % )、腹痛 ( 68.92 % )及发热 ,这些表现的发生率随病变范围加大而增高 ,病变范围以直肠炎、乙状结肠炎多见 ( 50 .68% )。全结肠炎患者病程 5a以上者明显多于 5a以下者 ( p<0 .0 5)。结论 :UC有较明显的临床特征 ,其病变范围与病程密切相系 ,且由结肠远端向近端发展 ,肠镜检查有助于诊断
Objective: To investigate the clinical features of ulcerative colitis (UC) and to improve the understanding and diagnosis and treatment of this disease. Methods: The clinical features of 148 patients with UC diagnosed by fiber colonoscopy from1995 to 1997 were retrospectively analyzed. Results: The incidence of UC in hospitalized patients was higher than that in the previous years. There was no significant difference between male and female patients. The mean age of onset was 40.37 years old and 30-49 years old. The clinical features include diarrhea (80.41%), pus and blood stool (63.51%), abdominal pain (68.92%) and fever. The incidence of these manifestations increased with the extent of the lesion. The extent of the lesion was more common in proctitis and sigmoiditis 50 .68%). Patients with total colitis over 5a were significantly more than 5a (p <0.05). Conclusions: UC has obvious clinical features, the scope of the lesion is closely related with the course of the disease, and it is developed from distal to proximal colon, and colonoscopy is helpful for the diagnosis