氟是人体必需的微量元素 ,但摄入过多的氟则会造成斑釉齿、氟骨症。我国规定牙膏中氟化物的最大允许浓度为 0 15%。目前 ,我国对化妆品中氟的测定主要采用茜素络合酮法[1] ,此法需要对样品进行蒸馏预处理。而选用离子电极法测定牙膏中氟 ,由于电极对待测离子有选择性响应 ,对 Fluorine is an essential trace element of the human body, but excessive intake of fluoride will cause spot glaze teeth, skeletal fluorosis. China’s provisions of fluoride in toothpaste, the maximum allowable concentration of 0 15%. At present, the determination of fluoride in cosmetics in China mainly uses alizarin complexation ketone method [1], this method requires the sample pretreatment distillation. The selection of ion-electrode method for the determination of fluoride in toothpaste, due to the selective reaction of the electrode to the ions to be measured, the