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目的探讨子宫肉瘤的临床特点和预后影响因素。方法回顾性分析接受手术治疗且随访资料完整的53例子宫肉瘤患者,子宫内膜间质肉瘤15例,平滑肌肉瘤38例,分析其临床特点、治疗及影响其预后的相关因素。结果平滑肌肉瘤为主要病理组织类型;5年生存率为30.0%;临床分期、分化程度、淋巴结转移是影响预后的独立危险因素(均P<0.05)结论子宫癌肉瘤总体预后较差,手术切除是子宫内膜肉瘤主要治疗方法;临床分期晚、分化程度低、淋巴结转移是子宫肉瘤预后不良的标志。
Objective To investigate the clinical characteristics of uterine sarcoma and prognostic factors. Methods The clinical data of 53 cases of uterine sarcoma, 15 cases of endometrial stromal sarcoma and 38 cases of leiomyosarcoma who underwent surgery were retrospectively analyzed. The clinical features, treatment and prognostic factors were analyzed. Results The leiomyosarcoma was the main pathological type. The 5-year survival rate was 30.0%. The clinical stage, differentiation and lymph node metastasis were independent risk factors for prognosis (all P <0.05). Conclusion The overall prognosis of uterine carcinosarcoma is poor. Surgical resection is The main treatment of endometrial sarcoma; clinical stage late, low differentiation, lymph node metastasis is a sign of poor prognosis of uterine sarcoma.