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口腔颌面部感染是指口腔、颈部、面部软组织出现感染的常见病,由于颌面部存在许多肌筋膜间隙,一旦出现感染极易在间隙间相互扩散,出现多间隙感染,进而导致败血症、静脉炎、脑脓肿和纵膈炎等严重疾病,甚至危及生命.近年来,随着医学技术的不断发展,对颌面部间隙感染的相关研究逐渐丰富,本文就颌面部感染部位及来源、扩散途径、微生物学研究,诊断方法及治疗,以及口腔颌面部创伤后整形美容修复中如何预防颌面部间隙感染等方面的研究进行综述.“,”Oral and maxillofacial infection refers to the oral,neck,facial soft tissue infections common.As the maxillofacialregion is divided into many myofascial space,due to the potential connections of fascial spaces,infections can spread fromone space to another.Multiple space infection could lead to sepsis,phlebitis,brain abscess and mediastinal inflammation andsome other serious diseases,which could be life-threatening.In recent years,with the development of medical technology,theresearches on facial space infection has been gradually enriched.In this article,we reviewed literatures evaluated the locationand origin of maxillofacial infections,the ways of diffusion,related researches of microbiology and the diagnosis and treatment.