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采用离体血管实验观察到尼群地平能使冠状血管松弛，这件松弛作用与血管内皮完整与否无关．同时．我们还观察到，尼群地平可抑制培养的动脉平滑肌细胞的增殖．提示尼群地平舒张血管和抑制血管平滑肌增殖，可能是其抗实验性动脉粥样硬化作用的重要机制之一．
Using ex vivo vascular experiments observed that nitrendipine can relax coronary vessels, this relaxation and vascular endothelial integrity has nothing to do. Simultaneously. We also observed that nitrendipine inhibits the proliferation of cultured arterial smooth muscle cells. It is suggested that nitrendipine can relax blood vessels and inhibit the proliferation of vascular smooth muscle cells, which may be one of the important mechanisms of anti-atherosclerosis.