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目的观察胺碘酮治疗急性心肌梗死后室性心律失常的临床疗效。方法选择2015年1月-2016年1月医院收治的急性心肌梗死后室性心律失常患者74例,随机分成试验组和对照组各37例。对照组采用利多卡因治疗,试验组采用胺碘酮治疗,均连续用药治疗7d后,对比分析2组的临床效果。结果治疗后,试验组总有效率为94.6%高于对照组的86.5%,差异有统计意义(P<0.05);与治疗前相比,2组患者的室性心律失常出现次数、QRS波时间都有一定改善,试验组更优于对照组,差异有统计学意义(P<0.05);试验组的不良反应情况要优于对照组,差异有统计意义(P<0.05)。结论在急性心肌梗死后室性心律失常临床治疗中,采用胺碘酮治疗,疗效显著,可有效改善临床症状,不良反应较少,安全性较高,具有重要临床意义。
Objective To observe the clinical effect of amiodarone on ventricular arrhythmias after acute myocardial infarction. Methods Totally 74 patients with ventricular arrhythmia after acute myocardial infarction hospitalized from January 2015 to January 2016 were randomly divided into experimental group and control group (n = 37). The control group was treated with lidocaine, and the experimental group was treated with amiodarone. After continuous treatment for 7 days, the clinical effects of the two groups were compared. Results After treatment, the total effective rate in the experimental group was 94.6%, which was significantly higher than that in the control group (86.5%, P <0.05). Compared with those before treatment, the incidence of ventricular arrhythmia, QRS wave time (P <0.05). Adverse reactions in the experimental group were better than those in the control group, with statistical significance (P <0.05). Conclusions In the clinical treatment of ventricular arrhythmia after acute myocardial infarction, the use of amiodarone treatment, significant effect, which can effectively improve the clinical symptoms, fewer adverse reactions, high safety, has important clinical significance.