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本文用高压液相色谱内标定量法测定尼可地尔在兔中的血药浓度。其最低检出限度为20ng/ml,变异系数为4.2%,回收率为97.05%。此法重现性好,灵敏度较高。
In this paper, high-pressure liquid chromatography quantitative determination of nicorandil in rabbits blood concentration. The lowest detection limit of 20ng / ml, the coefficient of variation of 4.2%, the recovery rate was 97.05%. This method reproducibility, high sensitivity.