治疗药物监测(ＴＤＭ)是最近二十多年来在治疗医学领域内崛起的一门新的边缘学科,其目的是提高临床用药的有效性与安全性。其重要的手段就是通过测定血液或其他体液中药物浓度,利用药代动力学的原理和公式使给药方案个体化,以提高药物的疗效,避免或减少毒性反应,同时也为药物中 Therapeutic drug monitoring (TDM) is a new fringe discipline that has emerged in the therapeutic medicine field for more than two decades with the aim of improving the efficacy and safety of clinical medication. The important method is to determine the drug concentration in blood or other bodily fluids and to use pharmacokinetic principles and formulas to individualize the drug regimen so as to improve the curative effect of the drug and to avoid or reduce the toxic reaction,