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70年代后期,Farall等为寻找新型正性肌力药以替代强心试和儿茶酚胺,筛选了一系列化合物。首先研制成功的是氨力农(amrlnon)。其后15年中又有一系列药物问世。业已证明,新型正性肌力药可改善急性心衰患者的血流动力学,提高慢性心衰患者的生活质量。然而,这类药物能否延长
In the late 1970s, Farall et al. Screened a series of compounds in search of a new inotropic drug instead of tacrolimus and catecholamines. The first successful development was amrlnon. In the next 15 years a series of drugs came out. It has been demonstrated that the new inotropic agents improve hemodynamics in patients with acute heart failure and improve the quality of life in patients with chronic heart failure. However, whether such drugs can be prolonged