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目的临床比对观察制霉菌素联合碳酸氢钠和单用制霉菌素对小儿念珠菌性口炎的实际疗效。方法对照组80例,用制霉菌素溶液涂抹口腔。治疗组85例,在对照组常规治疗的基础上,给予2%碳酸氢钠溶液清洁口腔。2组均观察3d,随访1个月,比较两组疗效。结果治疗组有效率显著高于对照组(p<0.05),复发率显著低于对照组(p<0.05)。结论制霉菌素联合碳酸氢钠治疗小儿口腔念珠菌性口炎的疗效显著高于单用制霉菌素,且复发率低,在临床中应推广应用。
Objective To compare the clinical efficacy of nystatin with sodium bicarbonate and nystatin alone in children with candidal stomatitis. Methods 80 cases of control group, nystatin solution smear oral. The treatment group of 85 cases, in the control group on the basis of conventional treatment, given 2% sodium bicarbonate solution to clean the mouth. Two groups were observed 3d, followed up for 1 month, the two groups were compared. Results The effective rate of the treatment group was significantly higher than that of the control group (p <0.05), and the recurrence rate was significantly lower than that of the control group (p <0.05). Conclusion The efficacy of nystatin combined with sodium bicarbonate in the treatment of oral candidiasis in children is significantly higher than that of nystatin alone, and the recurrence rate is low. It should be widely used in clinical practice.