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目的了解深圳市5种人群的梅毒感染情况及确诊患者的治疗情况。方法对2014年进入研究场所的人员进行梅毒血清学检测,为确诊感染者提供转诊及治疗服务。结果研究对5种人群共157 137人进行了梅毒血清学检测,发现甲苯胺红不加热血清试验(TRUST)和梅毒螺旋体颗粒凝集试验(TPPA)均阳性533例,仅TPPA阳性474例,梅毒感染率为0.64%;其中艾滋病自愿咨询检测点求询者、社区药物维持治疗门诊服药者、献血人员、羁押人员和婚前检测人员的感染率分别是2.29%、4.09%、0.43%、0.39%和0.09%。本研究共为324例需转诊的现症梅毒患者提供了转诊服务,提供转诊服务率为79.41%(324/408);其中转诊到位185例,转诊到位率为57.10%。270例现症梅毒患者接受了抗梅毒治疗。结论本研究在不同的梅毒监测试点初步建立了检测-治疗-管理的梅毒防治工作机制,确诊患者接受治疗率较低;需进一步完善转诊机制,促进患者转诊到位,从而提高梅毒患者的治疗率。
Objective To understand the syphilis infection and the treatment of patients diagnosed in 5 kinds of people in Shenzhen. Methods A syphilis serological test was conducted on the persons entering the research site in 2014 to provide referral and treatment services for the confirmed infected persons. Results A total of 157 137 individuals from 5 different populations were tested for syphilis serology and found that TRUST and TPPA were positive in 533 cases and only TPA positive in 474 cases and syphilis infection The prevalence rate was 0.64%. Among them, the prevalence rates of HIV voluntary counseling and testing sites, community-based drug maintenance and treatment outpatients, blood donors, detainees and premarital examiners were 2.29%, 4.09%, 0.43%, 0.39% and 0.09 %. In this study, 324 cases of patients with syphilis who were referred were retrospectively served, with a referral service rate of 79.41% (324/408). Of these, 185 cases were referred and the referral rate was 57.10%. 270 cases of syphilis patients received anti-syphilis treatment. Conclusion In this study, syphilis prevention and control work mechanism of detection-treatment-management was initially established in different syphilis monitoring pilots. The treatment rate of patients diagnosed with syphilis was low. The mechanism of referral should be further improved to promote the referral of patients so as to improve the treatment of syphilis patients rate.