关于内毒素的性质和病理作用不少人正在深入研究,认为它是一种多糖—类脂—蛋白质复合物,除了具有一般的免疫源性和毒性外,亦具有热源性。侵入机体的细菌死亡破裂后即可释放其内毒素,它能直接作用于机体的体温调节中枢,使体温调节机能紊乱,引起发热,另外也可以作用于多形核白细胞或巨噬细胞,使释放内源性致热原作用于体温调节 Many people are delving into the nature and pathology of endotoxin, considering it to be a polysaccharide-lipid-protein complex that, in addition to its general immunogenicity and toxicity, is also pyrogenic. Bacteria that invade the body can rupture and release endotoxin, which can directly act on the body’s thermoregulatory center, causing the body temperature to regulate dysfunction and cause fever. In addition, it can also act on polymorphonuclear leukocytes or macrophages to release Endogenous pyrogen effect on thermoregulation