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为观察国产盐酸洛美沙星滴眼液治疗眼部细菌感染性疾病的临床疗效、适应证及不良反应。我们应用前瞻性评估研究方法,按随机分配原则将所研究的150例分为试验组(100例)及对照组(50例),分别投以盐酸洛美沙星滴眼液和盐酸环丙沙星滴眼液,在统一标准下观察其临床效应。结果显示洛美沙星滴眼液对眼部细菌性炎症(包括细菌性结膜炎、细菌性角膜炎、慢性泪囊炎、麦粒肿、睑缘炎)的临床治愈率、总有效率、细菌清除率均与环丙沙星滴眼液无显著性差异(X2检验,P>005),且未发现明显的毒副作用。
To observe the clinical efficacy, indications and adverse reactions of domestic Lomefloxacin Eye Drops in the treatment of ocular bacterial infections. We applied the prospective assessment of research methods, according to the principle of random allocation of the 150 cases were divided into the experimental group (100 cases) and the control group (50 cases), were cast with lomefloxacin hydrochloride eye drops and ciprofloxacin hydrochloride Eye drops, observed in a uniform standard clinical effect. The results showed that lomefloxacin eye drops on the ocular bacterial inflammation (including bacterial conjunctivitis, bacterial keratitis, chronic dacryocystitis, sty, blepharitis) clinical cure rate, total effective rate, bacterial clearance rate And ciprofloxacin eye drops no significant difference (X2 test, P> 0 05), and found no significant side effects.