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急性视网膜坏死(acute retinal necrosis,ARN)综合征是某些疱疹病毒感染眼后段的特殊临床表现。典型的ARN综合征三联征包括:(1)视网膜、脉络膜的动脉炎和静脉炎;(2)好侵犯周边部视网膜的融合性、坏死性视网膜炎;(3)中度到重度的玻璃体炎。眼前段炎症、视神经炎和晚期出现的视网膜脱离也常见于本病。目前已确证至少有2个疱疹病毒族的成员是本征的病因,即带状水痘病毒(VZV)和单纯疱疹病毒(HSV)。本文总结了ARN综合征的临床表现和当前推荐的治疗措施,着重于使患者视力预后得到明显改善的新近进展。
Acute retinal necrosis (ARN) syndrome is a specific clinical manifestation of the posterior segment of the eye in certain herpes viruses. Typical ARN syndrome triads include: (1) retinal, choroidal arteritis and phlebitis; (2) good infiltration of peripheral retinal fusion, necrotizing retinitis; (3) moderate to severe vitritis. Anterior segment inflammation, optic neuritis and retinal detachment are also common in this disease. It has now been confirmed that at least two members of the herpes virus family are intrinsic causes of VZV and HSV. This article summarizes the clinical manifestations of ARN syndrome and the current recommended treatment, focusing on making patients with visual acuity was significantly improved the recent progress.