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帕金森氏病（Ｐａｒｋｉｎｓｏｎ’ｓ ｄｉｓｅａｓｅ，ＰＤ）是一种常见的神经系统退行性疾病，其治疗方案颇多。各国学者进行了药物治疗，脑内细胞或组织移植治疗，基因治疗、以及立体定向毁损多巴胺神经传导通路治疗等等。近年来，脑内移植研究成果丰硕，尤其是胶囊化细胞移植取得了可喜的成就。ＰＣ１２细胞作为一种多巴胺释放细胞，在治疗ＰＤ时很有应用价值。本文综述了胶囊化ＰＣ１２细胞移植治疗ＰＤ的最新进展，提出该方案应用前景及展望。
Parkinson’s disease (PD) is a common degenerative disease of the nervous system and has many treatment options. National scholars conducted drug treatment, intracerebral cell or tissue transplantation therapy, gene therapy, and stereotaxic destruction of dopamine nerve conduction pathway therapy and so on. In recent years, brain transplantation research has achieved fruitful results, especially in the grafted cell transplantation has made gratifying achievements. PC12 cells, as a dopamine-releasing cell, are of great value in the treatment of PD. This review summarizes the recent advances in the treatment of PD with encapsulated PC12 cells and presents its application prospects and prospects.