论文部分内容阅读
目的探讨益气活血汤联合二甲双胍治疗2型糖尿病患者的临床疗效。方法将68例初发肥胖的2型糖尿病患者随机分为两组,每组34例,对照组给予二甲双胍,观察组给予益气活血汤联合二甲双胍治疗,两组均连续治疗12周,检查两组患者空腹血糖(FBG)、餐后2 h血糖(PBG)、糖化血红蛋白(HbA1c)及TG、TC、HDL-C、BMI的变化并统计不良反应发生情况。结果治疗后两组FPG、PBG、HbA1c及BMI水平均明显下降,与治疗前比较差异有统计学意义(P<0.05);观察组治疗后FPG、PBG、HbA1c及BMI水平均低于同期对照组水平,两组比较差异有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义(P>0.05)。结论益气活血汤联合二甲双胍治疗2型糖尿病的临床疗效确切,不良反应小,值得推广应用。
Objective To investigate the clinical efficacy of Yiqi Huoxue Decoction combined with metformin in type 2 diabetic patients. Methods 68 cases of newly diagnosed obese type 2 diabetic patients were randomly divided into two groups, 34 cases in each group, the control group were given metformin, the observation group was given Yiqi Huoxue Decoction combined with metformin treatment, both groups were treated for 12 weeks, two groups were examined The fasting blood glucose (FBG), postprandial 2h blood glucose (PBG), HbA1c, TG, TC, HDL-C and BMI were measured and the occurrence of adverse reactions were calculated. Results The levels of FPG, PBG, HbA1c and BMI in the two groups were significantly decreased after treatment (P <0.05), and the levels of FPG, PBG, HbA1c and BMI in the observation group were lower than those in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Yiqi Huoxue Decoction combined with metformin in the treatment of type 2 diabetes has definite curative effect and little adverse reaction, which is worth popularizing and applying.