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[目的]探讨经口内镜下肌切开术(POEM)对贲门失弛缓症患者(AC)生活质量的影响。[方法]选取47例接受POEM的AC患者作为研究对象,于术前以及术后1个月、6个月和12个月使用AC疾病特异性生活质量问卷、Eckardt评分系统和食管测压对患者进行评估。[结果]AC患者POEM后疾病特异性生活质量、Eckardt评分均较术前显著改善(P<0.01),食管下括约肌静息压力显著下降(P<0.05)。术前和术后疾病特异性生活质量均与Eckardt评分呈正相关。[结论]POEM能有效改善AC患者生活质量,控制症状对提高患者生活质量具有积极意义。
[Objective] To investigate the effect of POEM on the quality of life in achalasia patients. [Methods] Forty-seven AC patients receiving POEM were enrolled in this study. Patients with AC disease-specific quality of life questionnaire, Eckardt score system and esophageal manometry were preoperatively and 1 month, 6 months and 12 months after operation. to evaluate. [Results] The disease-specific quality of life and Eckardt score of PO patients were significantly improved (P <0.01) and the resting pressure of lower esophageal sphincter was significantly decreased (P <0.05). Preoperative and postoperative disease-specific quality of life were positively correlated with Eckardt score. [Conclusion] POEM can effectively improve the quality of life of patients with AC, and the control of symptoms has positive significance to improve the quality of life of patients.