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0引言中药药代动力学研究近年来得到迅速发展.丹参注射液是我国独立研发的活血化瘀中药注射液,具有改善心肌缺血、增加冠脉流量、抗血栓、保肝等作用.我们应用高效液相色谱法同时测定血浆样品中丹参素、原儿茶酸、原儿茶醛、丹酚酸B四种有效成分含量,并研究其在家兔体内的药代
0 Introduction Chinese pharmacokinetic study has been rapidly developed in recent years.Danshen injection is an independent research and development in our country blood circulation Chinese medicine injection, with the improvement of myocardial ischemia, increase coronary flow, anti-thrombosis, liver protection and other effects. We use Simultaneous Determination of Danshensu, Protocatechuic Acid, Protocatechuic Acid and Salvianolic Acid B in Plasma Samples by High Performance Liquid Chromatography and Their Pharmacokinetics in Rabbits