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乳腺癌的生物学行为多种多样,籍此颇难推测病人的预后。迄后认为腋下淋巴结受侵程度是估计预后的最好指征之一。然而这只能在手术切除淋巴结后方可得知。基于当前不少患者只以姑息性外科手术治疗,因此极需一种自原发性肿瘤中得到估计预后资料的方法。本文报道利用肿瘤细胞中抗原状况作为估计预后的方法及其结果和意义。作者从175例患者获取原发性肿瘤标本,利用间接免疫过氧化物酶(immunoperoxidase)技术使两种单克隆抗体(HMFG-1,HMFG-2)
The biological behavior of breast cancer varied, it is difficult to speculate the patient’s prognosis. Later considered the degree of involvement of axillary lymph nodes is one of the best indications of prognosis. However, this can only be seen after surgical removal of the lymph nodes. Based on the fact that many patients are currently treated only with palliative surgery, there is a great need for a method of estimating prognostic data from primary tumors. This article reports the use of antigenic status in tumor cells as a means of assessing prognosis and its implications and implications. The authors obtained primary tumor samples from 175 patients and administered two monoclonal antibodies (HMFG-1, HMFG-2) using indirect immunoperoxidase