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目的观察一贯煎联合拉米夫定治疗肝肾阴虚型慢性乙型肝炎患者的临床疗效。方法随机将60例患者分为一贯煎联合拉米夫定的治疗组(31例)和单纯口服拉米夫定的对照组(29例),经治疗48个月及随访24个月,观察两组患者肝功能、HBVDNA定量、临床症状、总有效率。结果治疗组在治疗后及随访期其肝功能复常率、改善临床症状、降低耐药发生率、总有效率等,与对照组相比,差异有显著性意义。结论一贯煎对慢性乙型肝炎肝肾阴虚型患者肝功能、改善临床症状,减少拉米夫定的发生有一定疗效。
Objective To observe the clinical efficacy of omeprazole combined with lamivudine in the treatment of chronic hepatitis B patients with liver, kidney and yin deficiency. Methods A total of 60 patients were randomly divided into treatment group (n = 31) and lamivudine control group (n = 29). After 48 months of treatment and 24 months of follow-up, Group of patients with liver function, HBVDNA quantitative, clinical symptoms, the total effective rate. Results The treatment group after treatment and follow-up of liver function rate, improve clinical symptoms, reduce the incidence of drug resistance, the total effective rate, compared with the control group, the difference was significant. Conclusion Consistently fried on liver function in patients with chronic hepatitis B liver-kidney deficiency, improve clinical symptoms and reduce the incidence of lamivudine have a certain effect.