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一般资料24例均系1986年1月～1996年12月间住院 的病人,过去无癫痫发作,应用抗精神病药物过程中出现的癫痫发作者。其中男8例,女16例。年龄17～50岁,病程最短1个月,最长28年,诊断精神分裂症18例,抑郁症4例,分裂情感性精神病2例。 临床资料 1.诱发癫痫发作的药物和剂量24例中有18例为单一用药,6例合并用药。在诱发癫痫发作的药物中,以氯氮平诱发者为多,占全部病例的45.83%(11例),发作时剂量为125～700mg/日,平均为375mg/日;其次为氯丙嗪,占全部
General information 24 cases were from January 1986 to December 1996 hospitalized patients, the past without seizures, the application of antipsychotic drugs appeared in the process of seizures. There were 8 males and 16 females. Aged 17 to 50 years old, the shortest duration of 1 month, up to 28 years, 18 cases of schizophrenia diagnosed, 4 cases of depression, emotional schizophrenia in 2 cases. Clinical data 1. Induction of seizures in the drug and dose of 24 cases, 18 cases were single, 6 cases of combined medication. Among the drugs that induced seizures, clozapine was the most predominant, accounting for 45.83% (11 cases) in all cases and the dose was 125-700 mg / day at the time of attack, with an average of 375 mg / day, followed by chlorpromazine, For all