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目的丹参冻干粉针联合神经节苷酯治疗新生儿缺氧缺血性脑病的疗效观察。方法对照组50例,严格按照新生儿缺氧缺血性脑病治疗方案的三项维持、三项对症疗法进行治疗,并给予纠酸、能量合剂、胞磷胆碱等综合治疗;治疗组50例,在对照组的基础上加用10%葡萄糖30ml加丹参冻干粉针0.2g;10%葡萄糖30ml加单唾液酸四己糖神经节苷酯20mg,静脉滴注,1次/d,14d为一疗程。结果治疗组显效30例,有效15例,无效5例,总有效率90%;对照组显效24例,有效13例,无效13例,总有效率75%。差异有统计学意义(P<0.05)。结论丹参冻干粉针联合单唾液酸四己糖神经节苷酯治疗新生儿缺氧缺血性脑病,安全有效,值得推广。
Therapeutic effect of Danshen freeze - dried powder combined with ganglioside on neonatal hypoxic - ischemic encephalopathy. Methods 50 cases of control group, in strict accordance with neonatal hypoxic-ischemic encephalopathy treatment of three maintenance, three symptomatic therapy for treatment, and given correction acid, energy mixture, citicoline and other comprehensive treatment; the treatment group of 50 patients , On the basis of the control group plus 10% glucose 30ml plus freeze-dried Salvia Salvia 0.2g; 10% glucose 30ml plus monosialotetrahexosyl ganglioside 20mg, intravenous infusion, 1 / d, 14d A course of treatment. Results In the treatment group, 30 cases were markedly effective, 15 cases were effective, 5 cases were ineffective and the total effective rate was 90%. In the control group, 24 cases were markedly effective, 13 were effective, 13 were ineffective and the total effective rate was 75%. The difference was statistically significant (P <0.05). Conclusion Danshen freeze-dried powder combined with monosialin tetrahexose ganglioside in the treatment of neonatal hypoxic-ischemic encephalopathy, safe and effective, it is worth promoting.