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目的分析江门市计划生育服务中心抗感染药不良反应(ADR)发生的特点和规律。方法对我院2007年1月—2009年l2月收集到的218例抗感染药ADR报告分别从患者年龄、性别、给药途径、药品种类、累及器官或系统及临床表现等方面进行统计、分析。结果 218例抗感染药ADR报告涉及9类药品,其中β内酰类抗生素引起的ADR比例最大,其次为喹诺酮类药物。静脉给药较其他给药途径更易发生ADR。结论必须加强药品不良反应监测,规范使用抗感染药,促进临床的合理用药。
Objective To analyze the characteristics and regularity of occurrence of ADR in family planning service center of Jiangmen City. Methods The ADRs of 218 anti-infectives collected in our hospital from January 2007 to January 2009 were analyzed statistically from the aspects of patient’s age, sex, route of administration, type of drug, organs involved, system and clinical manifestation . Results 218 cases of ADRs reported anti-infectives involving 9 kinds of drugs, including β-lactam antibiotics caused by the largest proportion of ADR, followed by quinolones. Intravenous administration is more prone to ADR than other routes of administration. Conclusion We must strengthen the monitoring of adverse drug reactions, regulate the use of anti-infectives, and promote the rational use of clinical medicine.