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目的 :探讨灵芝煎剂对亚稀褶黑菇中毒患者的治疗作用。方法 :以前一年同种中毒病例 11例为对照 (对照组给予输氧、输液等常规治疗 )。治疗组 14例在常规治疗基础上 ,加用灵芝煎剂口服。比较两组的临床疗效及反映肾脏损害的尿N 乙酰 β D葡萄糖酐酶 (NAG)、尿红细胞和尿蛋白、反映肝脏损害的血清ALT、反映心脏损害的血清AST等各项指标改变情况。结果 :治疗组临床愈显率明显优于对照组 (P <0 0 1) ;治疗组绝大部分病例尿红细胞在治疗 2 4h后完全消失 ,尿蛋白也明显减少 ,而 3项酶学指标第 3天上升达高峰 ,以后逐渐下降 ;对照组各项指标则呈持续进行性上升 ,两组在相同时间各项指标比较 ,治疗组明显低于对照组 ,差异有显著性 (P <0 0 1)。结论 :灵芝煎剂对亚稀褶黑菇有较好的治疗作用 ,能明显降低亚稀褶黑菇中毒的病死率。
Objective : To investigate the therapeutic effect of Lingzhi decoction on the poisoning of Pleurotus olivaceus. Methods: 11 cases of the same kind of poisoning in the previous year were used as controls (control group was given oxygen, infusion and other routine treatment). In the treatment group, 14 cases were treated with oral lingzhi decoction on the basis of routine treatment. The clinical outcomes of the two groups were compared, including changes in urinary N-acetyl-β-glucuronidase (NAG), urinary red blood cells and urine protein, renal ALT, and serum AST reflecting cardiac damage. Results: The clinical manifestation rate of the treatment group was significantly better than that of the control group (P <0 01). In most cases of the treatment group, the urinary erythrocytes completely disappeared after 24 hours of treatment, and the urinary protein was also significantly reduced, while the three enzymatic indicators were After 3 days, it reached the peak, then gradually decreased; the indicators in the control group continued to increase. The two groups at the same time compared the indicators, the treatment group was significantly lower than the control group, the difference was significant (P <0 0 1 ). Conclusion : Lingzhi decoction has a good therapeutic effect on the rare pleated black mushroom, and it can significantly reduce the mortality rate of poisoning of Pleurotus plicase.