jadR^＊ and jadR2 act synergistically to repress jadomycin biosynthesis

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：chinaprogram

【摘要】

：

The biosynthesis of antibiotics is controlled by cascade regulation involving cluster-situated regulators (CSRs) and pleiotropic regulators. Three CSRs have bee

【作者】

：

ZHANG YanYan ZOU ZhengZhong NI

【机构】

：

StateKeyLaboratoryofMicrobialResources,UniversityofChineseAcademyofSciences

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2013年7期

【关键词】

：

生物合成基因簇协同相互作用相互抑制压力信号 CSR 突变体稳压器 jadR^＊ jadR2 jadomycin biosynthesis clu

【基金项目】

：

supported by grants from the Ministry of Science and Technology of China （2013CB734001, 2009CB118905）, the National Natural Science Foundation of China （31270110, 31030003）

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The biosynthesis of antibiotics is controlled by cascade regulation involving cluster-situated regulators (CSRs) and pleiotropic regulators. Three CSRs have been identified in the jadomycin biosynthetic gene cluster, including one OmpR-type activator (Jad

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jadR^＊ and jadR2 act synergistically to repress jadomycin biosynthesis

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