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目的:探讨血清CA125和EMAb水平与子宫内膜异位症(EM)的相关性,为EM的评判提供临床依据。方法:选择EM患者70例及同期体检的健康女性70例,比较两组女性血清CA125和EMAb水平,同时探讨血清CA125和EMAb水平与EM分期的相关性及两者联合检测的临床意义。结果:EM患者血清CA125和EMAb水平显著高于健康女性,两者差异有统计学意义(P<0.01);EM患者中血清CA125水平与病变分期呈正相关性(P<0.01),血清EMAb水平与病变分期无相关性(P>0.05);两项指标的联合检查可显著提高EM检出的敏感性与特异性(P<0.01,P<0.05)。结论:血清CA125和EMAb可做为EM诊断与治疗效果观察的可靠指标,两者联合检查可提高敏感性与特异性。
Objective: To investigate the correlation between serum CA125 and EMAb levels and endometriosis (EM), and to provide a clinical basis for the evaluation of EM. Methods: Seventy patients with EM and 70 healthy women were enrolled in this study. Serum levels of CA125 and EMAb were compared between the two groups. The correlation between the level of serum CA125 and EMAb and the stage of EM and the clinical significance of the combined detection of the two were also explored. Results: The levels of serum CA125 and EMAb in patients with EM were significantly higher than those in healthy women (P <0.01). There was a positive correlation between serum CA125 level and pathological stage (P <0.01) No correlation was found between the two groups (P> 0.05). The combination of the two indexes could significantly increase the sensitivity and specificity of EM (P <0.01, P <0.05). Conclusion: Serum CA125 and EMAb can be used as reliable indicators for the diagnosis and treatment of EM. The combination of the two can improve the sensitivity and specificity.