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为了解江西省山区县健康人群风疹抗体水平 ,为制订风疹疫苗免疫策略提供科学依据 ,2 0 0 0年 4～ 8月选择交通相对闭塞、人口流动相对较少的江西省山区安远县作为调查点 ,对 8月龄～ 30岁健康人群采血检测风疹血球凝集抑制 (HI)抗体 ,同时对 2～ 4岁健康儿童接种国产BDRⅡ株风疹减毒活疫苗和进口麻疹、流行性腮腺炎、风疹(MMR)疫苗 ,观察其效果。共检测 8月龄～ 30岁健康人群血清 6 0 7份 ,阳性率 5 7 6 6 % ,抗体几何平均滴度(GMT)为 :1∶14 13。 2～ 4岁儿童接种国产风疹减毒活疫苗和进口MMR疫苗后 ,风疹抗体阳转率均为 10 0 % ,GMT分别为 1∶2 6 3 95、1∶197 4 0 ,两种不同疫苗风疹HI抗体GMT差异无显著的统计学意义
To understand the level of rubella antibody in healthy people in mountainous counties of Jiangxi Province and provide a scientific basis for formulating the immunization strategy of rubella vaccine, from April to August in 2004, we selected Anyuan County, a mountainous area in Jiangxi Province, relatively closed traffic and relatively few population movements At the same time, healthy children aged 2 to 4 years were vaccinated domestic live attenuated attenuated live BDR II strain vaccine and imported measles, mumps, rubella (rubella) MMR) vaccine, observe its effect. A total of 607 serum samples were collected from healthy people aged from 8 months to 30 years, the positive rate was 57.6%. The geometric mean antibody titer (GMT) was 1:14 13. 2 to 4 years old children vaccinated domestic live attenuated rubella vaccine and imported MMR vaccine, rubella antibody positive conversion rates were 10%, GMT were 1:2 6 3 95,1:197 4 0, two different vaccine rubella HI antibody GMT difference was not statistically significant