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目的：观察国产重组干扰素α２ｂ治疗慢性丙型肝炎的近期疗效。方法：应用长春生物制品研究所生产的ｒＩＦＮα２ｂ治疗４５例丙型肝炎患者，３００万单位肌肉注射，隔日１次，共３个月；另２４例患者给予一般保肝治疗作为对照组。结果：３个月后治疗组２７／４５ＡＬＴ复常，３５／４５ＨＣＶＲＮＡ阴转，和对照组比较差异有显著性。结论：国产重组干扰素α２ｂ在抗病毒和恢复肝功能方面均有较好疗效。
Objective: To observe the short-term curative effect of domestic recombinant interferon α-2b in the treatment of chronic hepatitis C Methods: 45 cases of hepatitis C patients were treated with rIFN2b produced by Changchun Institute of Biological Products. Three million units were injected intramuscularly every other day for 3 months. The other 24 patients were given general hepatoprotective therapy as control group. Results: After 3 months, the treatment group 27/45 ALT normalization, 35/45 HCV RNA negative conversion, compared with the control group, the difference was significant. Conclusion: Domestic recombinant interferon alpha 2b in the anti-virus and restore liver function have a good effect.