论文部分内容阅读
目的探讨EICU呼吸机相关性肺炎(VAP)的临床及病原学特点。方法对46例VAP患者的临床资料与病原菌的分布及耐药性进行回顾性研究与统计学分析。结果 98例人工气道机械通气患者中46例发生VAP,VAP发生率为46.9%;VAP组上机时间明显长于非VAP组;共检出病原菌134株,鲍曼不动杆菌、铜绿假单胞菌、嗜麦芽窄食单胞菌对头孢菌素及亚胺培南等各种常用抗生素耐药情况均十分严重。检出金黄色葡萄球菌23株,其中耐甲氧西林株(MRSA)20株,对万古霉素及替考拉宁全部敏感,但对其他抗生素耐药严重。结论 VAP是机械通气治疗失败的重要原因之一,防治VAP应重视消毒、无菌操作以及根据该病区细菌分布及耐药情况选择最佳经验治疗方案。
Objective To investigate the clinical and etiological characteristics of EICU ventilator-associated pneumonia (VAP). Methods The clinical data of 46 patients with VAP and pathogen distribution and drug resistance were retrospectively studied and statistically analyzed. Results The VAP occurred in 46 of the 98 patients with artificial airway mechanical ventilation and the VAP incidence was 46.9%. The VAP group was significantly longer than the non-VAP group. 134 pathogenic bacteria, Acinetobacter baumannii, Bacteria, Stenotrophomonas maltophilia on cephalosporins and imipenem and other commonly used antibiotics are very serious resistance. 23 strains of Staphylococcus aureus were detected, of which 20 strains of methicillin-resistant strains (MRSA) were all sensitive to vancomycin and teicoplanin, but were resistant to other antibiotics. Conclusion VAP is one of the important reasons for the failure of mechanical ventilation. VAP should pay attention to disinfection and aseptic operation and select the best experience treatment program according to the bacterial distribution and drug resistance in this ward.