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目的:通过测定各产地藏药南寒水石不同炮制品钙溶出率,揭示炮制对南寒水石钙溶出率的影响。方法:运用EDTA滴定法测定青海、西藏、甘肃、四川四省区产地藏药南寒水石生品、水淬品、酒淬品、酸酪淬品水煎液钙溶出率。结果:各种炮制方法均能显著提高藏药南寒水石水煎液钙溶出率,除黄南浪加和甘南合作美其乡的样品外,其余各产地南寒水石炮制品水煎液钙溶出率大小顺序均为酸酪淬品>酒淬品>水淬品。结论:通过测定和比较各产地藏药南寒水石不同炮制品的钙溶出率,为评价各产地南寒水石的品质、阐明南寒水石炮制机理和规范其炮制工艺提供了基础数据。
OBJECTIVE: To determine the effect of processing on the calcium dissolution rate of Southern Han Shuishi by determining the calcium dissolution rates of different processed products of Tibetan medicine south Han Shu stones from different producing areas. Methods: The EDTA titrimetric method was used to determine the calcium dissolution rate of the Tibetan medicine cold salty fish products, water quenching products, alcohol quenching products and pickled products in Qinghai, Tibet, Gansu and Sichuan provinces. Results: All kinds of processing methods could significantly improve the calcium dissolution rate of Tibetan medicine Southern Han Shuishi Decoction, except for the sample of Huangnanlang plus Gannan cooperation Meiqi Township, The order of all is the cheese quenched product> wine quenched product> water quenched product. CONCLUSION: The determination of calcium dissolution rate of different processed products of Tibetan medicine south Han Shu stones from different producing areas provides the basic data for evaluating the quality of southern Han Shu stones from different producing areas, and clarifying the processing mechanism of Nan Han stones and standardizing its processing technology.