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对４２例年龄１７岁～４０岁，妊娠１２周～２８周健康妇女进行研究，比较用米非司酮配伍米索前列醇引产（实验组）与传统的单膜腔穿刺引术（对照组）两者疗效，以获得终止中期妊娠的一种简单可行的方法。结果提示：实验组与对照组相比，从用药到胎儿及附属组织完全排出时间差异无显著性（Ｐ＞０．０５）；产时产后出血量差异无显著性（Ｐ＞０．０５）；胎儿及附属组织排出完整情况相似；副作用如恶心，呕吐，头晕等实验组校对照组多见。结论：米非司酮配伍米索前列醇可用于终止中期妊娠。
A total of 42 healthy women aged 17-40 years and 12 weeks to 28 weeks of gestation were studied. The comparison of mifepristone with misoprostol induction (experimental group) and traditional single-lumen perforation (control group) Efficacy of both to get a simple and feasible method of termination of mid-term pregnancy. The results showed that compared with the control group, there was no significant difference between the experimental group and the control group (P> 0.05), but there was no significant difference in the amount of postpartum hemorrhage between the experimental group and the control group (P> 0.05). Fetal and ancillary tissue discharge complete similar situation; side effects such as nausea, vomiting, dizziness and other experimental group more common in school control group. Conclusion: Mifepristone with misoprostol can be used to terminate the second trimester pregnancy.