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目的观察纳洛酮辅助治疗脑出血患者的临床疗效。方法选取该院2013年5月-2015年5月收治的脑出血患者80例,随机分为观察组和对照组各40例。对照组进行常规治疗,观察组在对照组的基础上给予纳洛酮治疗,比较2组患者的临床疗效及用药安全性。结果观察组总有效率为92.5%高于对照组的70.0%,差异有统计学意义(P<0.05)。治疗过程中2组均有失眠、食欲不振与腹胀等轻微不适,其中观察组出现1例(2.5%),对照组出现2例(5.0%),2组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论纳洛酮辅助治疗脑出血患者疗效理想,且安全可靠,值得普及推广应用。
Objective To observe the clinical effect of naloxone in the treatment of cerebral hemorrhage. Methods Eighty patients with ICH admitted from May 2013 to May 2015 in our hospital were randomly divided into observation group (40 cases) and control group (40 cases). The control group was treated routinely. The observation group was given naloxone on the basis of the control group. The clinical efficacy and safety of the two groups were compared. Results The total effective rate of the observation group was 92.5% higher than that of the control group (70.0%), the difference was statistically significant (P <0.05). There were 1 case (2.5%) in observation group and 2 cases (5.0%) in control group, there was no statistical difference in the incidence of adverse reactions between the two groups Significance (P> 0.05). Conclusion Naloxone adjuvant treatment of patients with cerebral hemorrhage ideal effect, and safe and reliable, it is worth popularizing the application.