论文部分内容阅读
近年来,人感染高致病性禽流感已成为危害公众健康的重要的人畜共患传染病。自1997年首次在香港发生了禽流感病毒感染人并致人死亡的病例后,禽流感病毒感染人的事例频发,并表现出多病毒亚型的趋势,其中H5N1、H7N9等亚型禽流感在人群中有不同程度的流行,虽然目前为止尚缺乏人与人之间直接传播的证据,但病毒的不断变异所形成的潜在威胁仍引起了全世界的重视,因此有效防控人禽流感疫情具有重大意义。本文就人禽流感在人群中流行需具备的必要条件、禽流感病毒感染人发病机制及综合性的防控措施、特异性疫苗研究和应急接种、药物防治等对策的文献进行整理综述。
In recent years, human infection with HPAI has become an important zoonotic disease that endangers public health. Since the first case of human bird flu virus death in Hong Kong in 1997, cases of human infection with avian influenza virus were frequent and showed a tendency of polyvirus subtypes. Subtype avian influenza such as H5N1 and H7N9 Although there is still no evidence of direct human-to-human transmission so far, the potential threat posed by the constant mutation of the virus still attracts worldwide attention and therefore effectively prevents and controls the outbreak of human bird flu has great significance. In this paper, the necessary conditions for the spread of human bird flu in the population, the pathogenesis of avian influenza virus infection and comprehensive prevention and control measures, specific vaccine research and emergency vaccination, drug prevention and treatment and other related literature review.