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根据高原缺氧作用特点配制高原Ⅱ(KY-Ⅱ)药物。经动物实验表明:与对照组比较,KY-Ⅱ号药可延长缺氧动物活存时间、活存数(P<0.05)和降低耗氧量(P<0.01)的基础上,选用18~25岁男性青年,分2批于大型低压舱内,减压至模拟海拔4000m高原停留48小时后,再继续减压至模拟5000m高原生活24小时(连续72小时)。将受试者随机分为2组,采取双盲法分别服用KY-Ⅰ(安慰剂)和KY-Ⅱ号药。实验期间,运用阻
Plateau Ⅱ (KY-Ⅱ) drugs were prepared according to the plateau hypoxia effect. Animal experiments showed that KY-Ⅱ could prolong the survival time, viability (P <0.05) and decrease oxygen consumption (P <0.01) of hypoxic animals compared with the control group, Year-old male youth, divided into 2 batches in a large low-pressure cabin, depressurized to a simulated altitude of 4000m plateau stay for 48 hours, and then continue to decompression to simulate a 5000m plateau for 24 hours (72 consecutive hours). Subjects were randomized into two groups and treated with KY-I (placebo) and KY-II in a double-blind fashion. During the experiment, the use of resistance