门脉性肝硬化的病理特点是肝细胞的变性、坏死、弥漫性纤维化和实质细胞的结节状再生,这三者互相综合改变了整个肝脏的解剖结构和血液循环,从而产生了典型的临床病理特征。但是一个正常的肝脏如何改建成为门脉性肝硬化的发展过程仍然存在着许多没有明确的问题。Moschcowitz认为门脉性肝硬化的前驱病变是肝脏的脂肪变性,以后在门脉区周围有淋巴细胞、浆细胞浸润和毛细血管增生,最后 The pathological features of portal cirrhosis are degeneration, necrosis, diffuse fibrosis of hepatocytes and nodular regeneration of parenchymal cells, which together alter the anatomy and circulation of the liver as a whole and result in typical Clinical and pathological features. However, there are still many problems that have not been clearly defined as how to rebuild a normal liver into the development of portal cirrhosis. Moschcowitz that the precursor of portal cirrhosis is the liver steatosis, later in the portal area around the lymphocytes, plasma cell infiltration and capillary proliferation, and finally