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目的:探讨毫米波、高压氧对机体免疫功能的影响及其可能机制。方法:将昆明种小鼠(n=60)双盲随机抽样分为2组,毫米波组(n=30)用频率36GHz,功率密度7.3～14.6W/m2的毫米波辐射荷瘤小鼠背部30min,1次/d,连续8d;对照组(n=30)在同等条件下进行假辐射。同种属小鼠(n=60)采用同种分组方法分为7组(每组n=10),其中6组经0.25MPa(绝对压)992mL/LO2的高压氧不同次数暴露,对照组在常压下以压缩空气持续通风,以上各组小鼠分别采用花环法测定红细胞C3b受体花环率(redbloodcell-C3breceptorrosettesrate,RCR,%),肿瘤细胞-红细胞花环率(tumour-redbloodcellrosetterate,TRR,%)及脾脏、胸腺淋巴细胞-肿瘤细胞花环率(tumourcell-lymphocyterosetterate,TLR,%)。结果:①在毫米波辐射后0d和6d时,辐射组RCR犤2.0±1.6和4.0±1.5犦,TRR犤3.3±1.0和3.8±1.5犦,TLR(胸腺:5.2±1.8和5.8±1.4;脾脏:2.7±1.0和6.2±1.8)与对照组相比,均无明显差异(t=0.928～2.431,P均>0.05);在3d时,辐射组RCR(7.0±1.6),TRR(6.5±1.6),TLR(胸腺:12.4±3.0;脾脏:11.7±2.3)显著高于对照组(t=6.328～7.195,P均<0.05)。②与对照组比较,高压氧暴露1,3,5d时RCR,TRR,TLR(脾脏、胸腺)显著降低(t=1.923～8.531,P<0.01～0.05),而暴露15,20d时逐渐回升,与对照
Objective: To investigate the effects of millimeter wave and hyperbaric oxygen on immune function and its possible mechanism. Methods: A double-blind random sample of Kunming mice (n = 60) was divided into two groups. The millimeter wave group (n = 30) was irradiated with millimeter wave radiation at a frequency of 36 GHz and a power density of 7.3-14.6 W / 30min, 1 time / d, continuous 8d; control group (n = 30) under the same conditions of false radiation. Allogeneic mice (n = 60) were divided into 7 groups (n = 10 in each group) by the same grouping method. Among them, 6 groups were exposed to hyperbaric oxygen of 992mL / LO2 at 0.25MPa (absolute pressure) The above groups of mice were respectively analyzed by rosette method for determination of red blood cell C3b receptor rosetterate (RCR,%), tumor cell-erythrocyte rosetterate (TRR,%) And spleen, thymic lymphocytes - tumor cell rosette rate (tumourcell-lymphocyterosetterate, TLR,%). Results: ① At 0 and 6 days after millimeter wave radiation, RCR 犤 2.0 ± 1.6 and 4.0 ± 1.5 犦, TRR 犤 3.3 ± 1.0 and 3.8 ± 1.5 辐, TLR (5.2 ± 1.8 and 5.8 ± 1.4), spleen (T = 0.928-2.431, P> 0.05). At 3 days, RCR (7.0 ± 1.6) and TRR (6.5 ± 1.6) in the radiation group were significantly higher than those in the control group ), TLR (thymus: 12.4 ± 3.0; spleen: 11.7 ± 2.3) was significantly higher than that of the control group (t = 6.328 ~ 7.195, P <0.05). ②Compared with the control group, RCR, TRR and TLR (spleen and thymus) were significantly decreased at 1, 3, 5 days after hyperbaric oxygen exposure (t = 1.923-8.531, P <0.01-0.05) And control