论文部分内容阅读
目的研究急性脊髓炎使用甲泼尼龙冲击疗法的临床效果及影响。方法选取80例我院2009.1~2013.12期间收治的急性脊髓炎患者,所有患者按随机抽样法分为两组各40例。其中40例患者使用甲泼尼龙冲击疗法进行治疗作为观察组,另40例患者使用地塞米松常规疗法进行治疗作为对照组。结果治疗后,观察组、对照组总有效率分别为92.5%、62.5%,差异显著,P<0.05;患者下地行走时间、肌力改善2级以上时间以及排尿恢复时间均优于对照组,P<0.05;且不良反应发生率为0%,低于对照组的7.5%,P<0.05。结论甲泼尼龙冲击疗法治疗急性脊髓炎效果显著,安全性高,起效快,值得临床应用及推广。
Objective To study the clinical effect and impact of methylprednisolone in acute myelitis. Methods Eighty patients with acute myelitis treated in our hospital from January 2009 to December 2013 were enrolled. All patients were divided into two groups according to random sampling method, 40 cases each. 40 patients were treated with methylprednisolone therapy as the observation group, and the other 40 patients treated with dexamethasone conventional therapy as the control group. Results After treatment, the total effective rate in the observation group and the control group was 92.5% and 62.5%, respectively, with significant difference (P <0.05). The patients’ walking time, strength improvement more than grade 2 and urination recovery time were better than the control group <0.05; and the incidence of adverse reactions was 0%, lower than 7.5% of the control group, P <0.05. Conclusion The effect of methylprednisolone in the treatment of acute myelitis is significant, safe, rapid onset, worthy of clinical application and promotion.