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目的:探讨非鳞状细胞来源声门下区肿物的临床特征,诊断、病理类型和治疗方法,提高对这一罕见疾病的认识。方法:分析3例非鳞状细胞来源声门下区肿物患者的临床资料,结合相关文献,总结非鳞状细胞来源的声门下区肿物的临床表现、诊断和治疗经验。结果:3例患者中,1例以声嘶为主要症状,2例以吸气性呼吸困难为主要症状;3例在明确诊断及解除喉梗阻后均行声门下区肿物切除手术,其中2例经口行支撑喉镜下手术切除,1例经颈部入路切开环甲膜后行肿物切除手术,均完整切除肿物。1例上皮-肌上皮癌患者采取术后放疗,疗效满意。3例随访至今,无复发。结论:声门下型非鳞状细胞来源肿物较为罕见,早期容易漏诊,临床上应对声门下区仔细检查。治疗该类疾病以手术切除为主,可根据肿物大小、范围选择适宜的手术方式。
OBJECTIVE: To investigate the clinical features, diagnosis, pathological types and treatment of nonsquamous cell-derived subglottic masses and to raise awareness of this rare disease. Methods: The clinical data of 3 patients with non-squamous cell origin in subglottic area were analyzed. Relevant literatures were reviewed to summarize the clinical manifestations, diagnosis and treatment experience of nonsquamous cell-derived subglottic tumor. Results: Of the 3 patients, 1 had hoarseness as the main symptom, 2 aspirated dyspnea as the main symptom, 3 had undergone the subglottic tumor resection after the definite diagnosis and the removal of laryngeal obstruction, of which 2 One case underwent resection of the laryngoscope under the mouth and one case underwent resection of the cricothyroid membrane through the neck. All the tumors were completely removed. One case of epithelial-myoepithelial carcinoma patients received postoperative radiotherapy, with satisfactory results. 3 cases were followed up till now, no recurrence. Conclusion: The subglottic non-squamous cell-derived tumor is relatively rare, early misdiagnosis, clinical response to subglottic area carefully examined. The treatment of such diseases mainly by surgical resection, according to the size of the tumor, the scope of the appropriate choice of surgical approach.