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目的:探讨药物流产术后子宫异常出血的中西医结合治疗方法即应用醋酸甲羟孕酮片口服序贯配伍中药方剂口服进行临床治疗的可行性。方法:收集2009年1月~2011年10月来我院计划生育门诊要求进行药物流产,排出胚胎组织后有子宫异常出血且B超检查证实宫腔内少量蜕膜残留(残留面积≤2cm3)患者172例。自愿接受非手术治疗患者86例为观察组,另选择同期同等条件下手术治疗行清宫术患者86例为对照组。比较两组子宫异常出血停止时间、复查B超情况、月经复潮时间、月经出血量及持续时间、安全性等比较。结果:药物流产后子宫异常出血非手术治疗即使用中西医结合方法与手术治疗即清宫术治愈率上无显著性差异(P>0.05),说明中西医结合治疗与清宫术治疗疗效基本相同。药物流产后子宫异常出血应用中西医结合治疗与手术清宫术治疗后月经复潮出血量及出血时间上基本相同,无统计学显著性差异(P>0.05),且安全性较好,无不良反应。结论:应用醋酸甲羟孕酮片配伍改良中药方剂口服进行药物流产后子宫异常出血的非手术治疗有效。
Objective: To investigate the treatment of abnormal uterine bleeding after medical abortion combined with traditional Chinese and Western medicine treatment that is the application of medroxyprogesterone acetate tablets sequential oral compatibility of traditional Chinese medicine prescription for clinical treatment feasibility. Methods: From January 2009 to October 2011, we asked the family planning clinic of our hospital for medical abortion, abnormal uterine bleeding after embryo tissue excretion and small amount of residual decidual cells (residual area≤2cm3) in the uterine cavity confirmed by B-mode ultrasonography 172 cases. 86 patients who voluntarily received non-surgical treatment were selected as the observation group. Another 86 patients undergoing hysteroscopic surgery under the same conditions were selected as the control group. Comparison of two groups of abnormal uterine bleeding stop time, review of B-case, menstruation, recuperation time, menstrual bleeding and duration, safety and other comparisons. Results: Non-surgical treatment of abnormal uterine bleeding after medical abortion that using the combination of traditional Chinese and Western medicine and surgical treatment of curettage cure rate was no significant difference (P> 0.05), that traditional Chinese and Western medicine treatment and curettage effect is basically the same. Uterine bleeding after medical abortion application of Integrative Medicine and surgery curettage after menstruation re-bleeding and bleeding time is basically the same, no statistically significant difference (P> 0.05), and the safety is good, no adverse reactions . Conclusion: The application of medroxyprogesterone acetate tablets combined with modified traditional Chinese medicine prescription for oral administration of non-surgical treatment of abnormal uterine bleeding after medical abortion.