论文部分内容阅读
目的在超声生物显微镜（ｕｌｔｒａｓｏｕｎｄｂｉｏｍｉｃｒｏｓｃｏｐｙ，ＵＢＭ）眼前段成像技术基础上设计活体人眼虹膜形态定量测量方法，并对其精确性进行评价。方法在ＡｕｔｏＣＡＤＶｅｒｓｉｏｎ１２软件的基础上设计ＵＢＭ图像辅助测量方法。对ＵＢＭ实时获取的活体人眼前段不同子午线的ＰＣＸ格式图像采用该软件进行进一步处理和定量测量，包括虹膜轮廓及特征线的提取，虹膜厚度、虹膜膨隆曲率、虹膜静息长度的测量。对同一操作者对同一眼的同一子午线ＵＢＭ图像获取及同一幅图的测量结果的一致性进行评价。对不同操作者间的测量结果进行比较。采用该方法对正常人的虹膜形态进行初步定量研究。结果ＵＢＭ获取图像的变异系数小于５％。同一操作者对同一幅图各测量指标测量的变异系数均小于５％，不同操作者间部分测量结果差异有显著性，但测量结果绝对值相差不大，各测量者测量结果的变异系数相当。２１岁以上的９６例（１９２只眼）正常人虹膜形态定量测量结果：虹膜静息长度３．６９９±０．３９７ｍｍ，虹膜曲率半径９．１０１±１．４０８ｍｍ，虹膜平均厚度０．４０６±０．０４２ｍｍ。结论活体人眼虹膜形态实时定量测量方法的精确度和重复性可满足活体人眼生理、病理生理及相关疾病研?
Objective To design a method for quantitative measurement of iris morphology in living human eyes based on the anterior segment imaging of ultrasound biomicroscopy (UBM) and to evaluate its accuracy. Methods Based on AutoCADVersion12 software to design UBM image aided measurement method. This software was used to further process and quantitatively measure PCX images of different meridian anterior segments acquired by UBM in real time, including the extraction of iris contour and feature line, the thickness of iris, the swelling of iris and the measurement of resting length of iris. The same operator on the same meridian UBM image acquisition and the same map of the measurement results were evaluated. Comparison of measurements between different operators. This method was used to study the iris morphology of normal people. Results The coefficients of variation of UBM images were less than 5%. The same operator of the same map of the measurement of the coefficient of variation of the measured variables were less than 5%, between different parts of the measured results were significant differences, but the absolute difference between the measured results is not significant, the measured coefficient of variation of the measurement results quite. The iris morphology of 96 normal subjects (21 eyes) over 21 years old: The resting length of iris was 3.699 ± 0.397mm, the radius of iris curvature was 9.101 ± 1.408mm, the average iris thickness was 0.406 ± 0 .042mm. Conclusion The accuracy and repeatability of real-time quantitative measurement of iris morphology in living human beings can meet the needs of human eye physiology, pathophysiology and related diseases.