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神经母细胞瘤是儿童最常见的恶性肿瘤之一 ,其细胞的分化潜能与临床预后有关。许多指标已广泛应用于神经母细胞瘤的诊断和治疗 ,MYCN基因是其中之一 ,且与高危病例组有关。由于其只在一部分高危病例中表达 ,评判价值不够完善。B myb基因在细胞的增殖 ,分化中扮演了重要
Neuroblastoma is one of the most common malignant tumors in children. The differentiation potential of the cells is related to the clinical prognosis. Many indicators have been widely used in the diagnosis and treatment of neuroblastoma, MYCN gene is one of them, and high-risk cases related. Because it is only expressed in some high-risk cases, the evaluation value is not perfect. B myb gene plays an important role in cell proliferation and differentiation