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目的:分析不同治疗方法对原发性肝癌根治术后复发及预后的影响,探讨其防治方法及疗效。方法:肝癌根治术后复发73例患者,依据治疗方法不同分为再次手术组21例,非手术治疗组45例(射频消融治疗23例、经皮肝动脉插管化疗栓塞治疗22例)和未治疗组7例,比较1,3,5 a生存率。结果:再次治疗组1,3,5 a生存率显著高于未治疗组(P<0.05),再次手术组1,3,5 a生存率高于非手术治疗组(P<0.05)。结论:肝癌根治术后复发仍采用以外科手术切除为主,局部微创治疗、生物治疗等多种方法的有机序贯综合治疗;且再治疗可提高术后生存率,手术再切除是局部复发首选治疗方法。
Objective: To analyze the effect of different treatment methods on the recurrence and prognosis of primary hepatocellular carcinoma (HCC) after radical surgery, and to explore its prevention and cure methods and curative effects. Methods: According to the different treatment methods, 21 cases were divided into reoperation group, 45 cases (23 cases treated by radiofrequency catheter ablation, 22 cases treated by percutaneous transhepatic arterial chemoembolization) and The treatment group of 7 cases, 1,3,5 a survival rate. Results: The 1,3,5-year survival rates in the re-treatment group were significantly higher than those in the untreated group (P <0.05). The 1,3,5-year survival rates in the reoperation group were significantly higher than those in the non-surgical group (P <0.05). Conclusion: The recurrence after radical operation of hepatocellular carcinoma still adopts organic sequential therapy with surgical resection, local minimally invasive treatment, biological therapy and many other methods; and re-treatment can improve the postoperative survival rate, surgical resection is local recurrence Preferred treatment.