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实验室饲养的6只猎犬,感染前粪检肠道寄生虫及血检微丝蚴均为阴性,每犬接种50条犬恶丝虫感染期幼虫。感染前和治疗后间隔1～3周采血分离血清贮于-70℃备用,感染后26周始血检微丝蚴并计数。于感染后47周给犬静脉注射thiacetarsamide 10 mg/4.5kg,每天2次,共3天,6周后口服左旋咪唑11mg/kg,5～7天,抗成虫治疗后16周即感染后63周重复thiacetarsamide治疗2天,6
6 hounds raised in the lab, fecal intestinal parasites before infection, and microfilariae of blood tests were all negative. Fifty dogs infected with Dirofilaria were inoculated with each larva. Pre-infection and post-treatment 1 to 3 weeks after separation of blood serum was stored at -70 ℃ for spare, after 26 weeks of infection blood test microfilariae and count. The dogs were given intravenous thiacetarsamide 10 mg / 4.5 kg at 47 weeks postinfection twice daily for 3 days, levamisole 11 mg / kg orally 6 weeks later, 5 to 7 days, 16 weeks after infection with the adult worms, ie 63 weeks after infection Repeat thiacetarsamide treatment for 2 days, 6