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目的:探讨轮状病毒性肠炎的临床特征,提高该病的诊断准确率。方法:回顾性分析感染轮状病毒的患儿50例的临床表现和化验检查结果。结果(:1)就诊年龄3月-24月不等;(2)轻度脱水35例(70%),中度偏重度脱水15例(30%),酸碱平衡紊乱15例(30%),神志改变抽搐5例(10%);(3)心肌酶CK-MB轻-中度升高18例(36%),同时谷丙转酶57-120U/L,谷草转酶60-230U/L,血糖低正常范围19例(38%),血糖高16例(33%),凝血功能异常11例(22%),肾功能损害5例(10%),大便轮状病毒抗原检测均阳性,肠道细菌培养无致病菌生长;(4)经过抗病毒、补液等治疗后评估50例中符合全身炎症反应综合征(SIRS)诊断18例(36%)、不符合32例(64%)。结论:急性胃肠炎最常见病原体为轮状病毒(RV),重症RV感染可伴有病毒血症,且由于SIRS的存在,可能导致多脏器的严重损害,更有极少数会发展为MODS,从而危及患儿生命,因此应予以重视。
Objective: To investigate the clinical features of rotavirus enteritis and improve the diagnostic accuracy of the disease. Methods: A retrospective analysis of 50 cases of children infected with rotavirus clinical manifestations and laboratory test results. (2) mild dehydration in 35 cases (70%), moderate partial severe dehydration in 15 cases (30%), acid-base balance disorder in 15 cases (30%), (10%); (3) 18 (36%) CK-MB mild-moderate elevation of myocardial enzymes, meanwhile, ALT of 57-120U / L and 60-230U / 19 cases (38%) had low normal blood sugar, 16 cases (33%) had hyperglycemia, 11 cases (22%) had coagulation abnormalities and 5 cases (10%) had renal dysfunction. The stool rotavirus antigen test was positive (4) 18 cases (36%) of 50 cases were diagnosed with systemic inflammatory response syndrome (SIRS) after antivirus and rehydration therapy, which did not accord with 32 cases (64%), ). CONCLUSION: The most common pathogen of acute gastroenteritis is rotavirus (RV). Severe RV infection may be associated with viraemia. Due to the presence of SIRS, it may lead to severe organ damage, and in rare cases it may develop into MODS , Thus endangering children’s lives, it should be taken seriously.