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目的:探讨和研究药学干预对临床合理使用喹诺酮类药物的实际应用效果。方法:选取该院2015年1月至2015年6月接受喹诺酮类药物治疗的150例患者,整个过程未实施药学干预,将其纳入对照组。并选择该院2015年7月至2015年12月接受喹诺酮类药物治疗的150例患者,整个过程实施药学干预,将其纳入观察组,采用回顾性统计分析观察两组喹诺酮药物的使用情况、患者耐药性情况以及各科室医生对药物使用原则方面的知晓情况。结果:对照组不合理使用喹诺酮类药比例36%、耐药性比例47.3%;观察组不合理使用喹诺酮类药比例7.3%、耐药性比例0.7%。对照组医生对药物使用原则方面的知晓率(72%)低于观察组(96%)(P<0.05)。结论:药学干预对临床合理使用喹诺酮类药物效果显著,可有效提升喹诺酮类药物的合理使用率,具有临床推广价值。
Objective: To investigate and study the practical application effects of pharmacy intervention on the rational use of quinolones in clinical practice. METHODS: A total of 150 patients receiving quinolones in our hospital from January 2015 to June 2015 were selected and included in the control group without any medical intervention. 150 patients receiving quinolones in the hospital from July 2015 to December 2015 were selected and the whole process was followed by medical intervention. The patients were enrolled in the observation group and retrospective statistical analysis was used to observe the use of quinolone. Drug resistance and the doctor’s knowledge of the principles of drug use in all departments. Results: In the control group, the rate of quinolones was 36% and the rate of drug resistance was 47.3%. In the observation group, the rate of quinolones was 7.3% and the rate of drug resistance was 0.7%. Control group doctors awareness of the principles of drug use (72%) was lower than the observation group (96%) (P <0.05). Conclusion: Pharmacological interventions have significant effects on the rational use of quinolones in clinical practice, which can effectively improve the rational use rate of quinolones and have clinical promotion value.