本综述的目的为概述能被透析或近年发展的吸附剂血液灌流所排除的毒物,并严格评价药物体外排除在治疗中毒中的作用,详细说明判断严重中毒患者何时需行药物体外排除的标准。排除毒素的透析技术1854年 Thomas Graham 断言,“透析”(是他首先引用的术语)将用于临床治疗,但直至1913年 Abel 等人才研制出第一台血液透析器,并用他们研制的“空心纤维人 The purpose of this review is to summarize the toxicants that are excluded from the hemoperfusion of adsorbents that can be dialyzed or developed in recent years and to critically evaluate the role of drug in vitro exclusion in the treatment of poisoning and to specify in detail the criteria for determining when patients with severe poisoning should be excluded in vitro . Dialysis Technology to Eliminate Toxins Thomas Graham asserted in 1854 that ”dialysis“ (the first term he quoted) would be used for clinical treatment but until 1913 Abel et al. Developed the first hemodialyzer and developed them ”Hollow fiber people