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目的探讨乌司他丁对重度烧伤后肝肾功能的保护作用。方法 118例重度烧伤患者随机分成对照组58例和治疗组60例。治疗组在烧伤后中药溶痂加用乌司他丁20万U+5%葡萄糖液250ml,静脉滴注,2次/d,连用7d。对照组仅做常规治疗,分别检测第1、3、5、7天患者肝肾功能指标,进行统计学处理。结果重度烧伤后中药溶痂对患者肝肾功能有损害作用,治疗组肝肾功能指标明显好于对照组,差异有统计学意义(P<0.05)。结论乌司他丁对重度烧伤患者中药溶痂后肝肾功能有较好的保护作用,减少并发症,提高治愈率。
Objective To investigate the protective effect of ulinastatin on liver and kidney function after severe burn. Methods A total of 118 patients with severe burn were randomly divided into control group (58 cases) and treatment group (60 cases). In the treatment group, 250 mg of ulinastatin plus 5% dextrose solution was added to the Chinese medicine dissolubial mucosa after intravenous infusion twice a day for 7 days. Control group only routine treatment, were detected on the 1st, 3rd, 5th and 7th days in patients with liver and kidney function indicators for statistical analysis. Results After the severe burn, the Chinese medicine dissolving callus had a damaging effect on the liver and kidney function. The liver and kidney function indexes of the treatment group were significantly better than those of the control group (P <0.05). Conclusion Ulinastatin has a good protective effect on liver and kidney function after dissolution of Chinese herbs in patients with severe burn, reducing the complications and improving the cure rate.